Additionally, the data suggest that anxiety disorders caused 44.5 million disability-adjusted life-years globally in 2020 ( 11). A recent systematic review estimated an additional 76.2 million cases of anxiety disorders globally (an increase of 25.6%). In addition, they can cause substantial impairment of quality of life ( 10).Īccording to the latest evidence, anxiety disorders are becoming more prevalent. Moreover, anxiety disorders are often undetected, undertreated, and associated with the global health-related, personal and societal burden. Different studies demonstrate lifetime prevalence rates of anxiety disorders ranging from 5.1 to 16.6% in general population, and from 7.2 to 19.5% in primary care ( 4– 9). Estimates of the prevalence of anxiety disorders vary widely across studies and population groups. They are receiving increasing attention because of their early onset as well as their tendency to recur and cause disability ( 2, 3). Anxiety disorders are the most prevalent mental disorders in the general population in the world and have a significant impact on the global burden of disease ( 1).